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Description

Daxid® is manufactured by Pfizer. Sertraline is an active constituent, an antidepressant belonging to a drug class of selective serotonin reuptake inhibitors (SSRIs), also known as second-generation antidepressants.

Indications:

- depression or MDD (major depressive disorder) (feeling sad, inability to sleep properly or to enjoy life as one used to);

- prevention of recurrence of depression in adults;

- social anxiety disorder in adults (social phobia – feeling of intense anxiety or distress in social situations like talking to strangers, speaking in front of groups of people etc.);

- obsessive-compulsive disorder (OCD) in adults, children and adolescents aged 6 -17 (being constantly troubled by obsessions, that are described as persistent ideas);

- post traumatic stress disorder (PTSD) in adults (occurs after a very emotionally traumatic incident and is similar to depression and anxiety);

- panic disorder in adults (being obsessed, symptoms similar to OCD);

- off-label treatment of PE (premature ejaculation or too early ejaculation within 1 minute after penetration; Sertraline is able to prolong the coitus by delaying ejaculation).

MOA (mechanism of action):

Sertraline works by slowing the reabsorption of serotonin in the brain. Serotonin is a chemical neurotransmitter, which sends electrical impulses from one neuron to the next. Normally, serotonin is quickly reabsorbed, but Sertraline lets the serotonin remain in the synaptic gap between neurons for a longer period of time. This allows the chemical to send additional messages to the receiving neuron, which results in improvement in mood.

Dosage

For depression and obsessive compulsive disorder in adults only: 50 mg once a day. The daily dose may be increased in 50 mg increments and at intervals of at least 1 week over a period of weeks. The maximum dose is 200 mg a day. Not recommended for use in children and adolescents under 18 years of age.

For panic disorder, social anxiety disorder and post-traumatic stress disorder in adults only: starting dose is 25 mg once a day. After one week, this should be increased to 50 mg once a day. The daily dose may then be increased in 50 mg increments over a period of weeks. The maximum dose is 200 mg daily.

For obsessive compulsive disorder in adolescents aged 13-17: starting dose is 50 mg daily.

For obsessive compulsive disorder in children aged 6-12: starting dose is 25 mg once a day increasing to 50 mg daily after 1 week. The maximum dose is 200 mg daily.

Not recommended for use in children under 6 years of age.

Treatment in children should be held under the doctor's supervision.

Treatment is determined by the doctor depending on the type of mental illness and its severity. Treatment of depression should usually continue for 6 months after improvement.

Precautions:

Be careful while taking Daxid® tablets if you have diabetes, as it may alter your blood glucose levels and your insulin/medication may need adjusting.

When stopping treatment with Daxid®, it is best to decrease the dose gradually over a period of several weeks or months to minimize the withdrawal reactions.

Avoid consuming alcohol while taking Daxid®.

Do not take Daxid® in combination with grapefruit juice, as this may increase the level of Sertraline in your body.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Daxid® to compensate the missed dose.

Overdose

If you take an overdose of Daxid®, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Daxid® are:

  • allergic reactions (wheeziness, difficulty in breathing or dizziness, swelling of the eyelids, face, lips or throat, rash, convulsions)
  • insomnia
  • dizziness
  • sleepiness
  • headache
  • diarrhoea
  • feeling sick
  • dry mouth
  • ejaculation failure
  • fatigue
  • sore throat
  • depression
  • anxiety
  • agitation
  • nervousness
  • decreased sexual interest
  • teeth grinding
  • numbness and tingling
  • shaking
  • muscle tense
  • abnormal taste
  • lack of attention
  • visual disturbance
  • ringing in ears

Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Daxid® if you are allergic to Sertraline or any of the other ingredients in the tablets.

Do not take Daxid® if you are taking or have taken monoamine oxidase inhibitor drug (MAOI) (selegiline, moclobemide), or MAOI-like drug (linezolid) for depression.

Do not take Daxid® you are taking pimozide (drug for the treatment of mental disorders like schizophrenia or psychosis).

Do not take Daxid® if you suffer from epilepsy, have a history of seizures. or are receiving ECT (electroconvulsive therapy).

Do not take Daxid® if you suffer or have suffered from manic depressive illness (bipolar disorder) or schizophrenia.

Do not take Daxid® if you have suffered from a bleeding disorder or have been taking anticoagulants (e.g. acetylsalicylic acid, warfarin).

Do not take Daxid® if you have or have previously had thoughts of harming or killing yourself.

Do not take Daxid® if you have serotonin syndrome, low sodium levels in your blood, liver disease, have or have a history of angle-closure glaucoma.

Daxid® is only for use in adults (over 18 years of age). It can only be used to treat children and adolescents aged 6-17 years old with obsessive compulsive disorder (OCD).

Daxid® is not recommended for use if you are pregnant, likely to become pregnant or are breastfeeding, until your doctor decides if this medication is right for you.

Do not drive or operate machinery while treatment with Daxid®.

Consult your doctor prior taking Daxid® if you are taking any of the following medications: amino acid tryptophan (for depression), diazepam (a sedative), lithium (for mania and depression), anesthetics (fentanyl), tricyclic antidepressants (imipramine), medications for schizophrenia and other mental disorders (perphenazine, levomepromazine, olanzapine), medications to treat diabetes (tolbutamide), cimetidine (for ulcers), non-steroidal anti-inflammatory drugs (NSAIDs), diuretics (water pills), medications to treat epilepsy (phenytoin, phenobarbital, carbamazepine), tramadol (a painkiller), sumatriptan (for migraine), fenfluramine (appetite suppressant), herbal remedy St. John’s Wort, drugs used to regulate the rate and rhythm of the heart (flecainide, propafenone, verapamil, diltiazem), drugs used to treat fungal infections (ketoconazole, itraconazole, posaconazole, voriconazole, fluconazole), drugs used to prevent nausea and vomiting after an operation or chemotherapy (aprepitant).

Target Point Shipping Method Tracking Delivery Time Price
Worldwide Shipping

Worldwide Shipping

Registered Mail  Not trackable 14-21 business days USD 20.00 per order
EMS  Trackable, where available 5-9 business days USD 30.00 per order

Delivery time is:

Registered Mail - 14-21 business days, price - USD 20.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 30.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

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Q: What is Daxid®?

A: Daxid® is an antidepressant used to treat various mental disorders in adults, including depression, social anxiety disorder, obsessive-compulsive disorder (OCD), post traumatic stress disorder (PTSD), panic disorder. Children and adolescents aged 6-17 with OCD can also be treated with Daxid®.

Q: Does Daxid® cause dependence?

A: Daxid® is not addictive. However, sudden stopping or decrease in dose of Daxid® may cause withdrawal reactions like dizziness, numbness, sleep disturbances, agitation or anxiety, headaches, nausea, vomiting and shaking. Consult the doctor regarding the use of Daxid® and discontinuation.

Q: Is Daxid® a stimulant?

A: No, it isn't. Daxid® is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It does not stimulate the brain but improves depression by increasing the levels of a chemical called serotonin in the brain.

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